Robot on Rails

Robot on Rails builds Undergrad, a robotic lab system that executes plain-language protocols on existing benches, verifies steps with vision and logs results without custom code. Founded in Boston in 2022 and incubated at MassRobotics, the bootstrapped company reports more than $2 million in revenue.

Facts

Segment: Lab Automation
Country: United States
Founded: 2022
Website: https://www.robotonrails.com/

Timeline

2025-12-16 - Partnership - Robot on Rails, OpenAI and Red Queen Bio test AI-directed wet-lab research - The collaboration connected GPT-5 protocol design with Robot on Rails hardware executing molecular-cloning experiments on a conventional lab bench. The AI-generated protocol improved the target metric 79-fold, while robotic execution produced a 2.13-fold… - source: robotonrails.com

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Team

Chase Olle - Founder & CEO
Nitin Mahadeo, Ph.D. - Lead Robotics & Perception
Azadeh Samadian - Head of AI, Data & Cloud Infrastructure

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Relations

OpenAI - AI Directed Wet Lab Research - Robot on Rails worked with OpenAI and Red Queen Bio on an AI-directed wet-lab molecular-cloning system.
Red Queen Bio - Wet Lab Research Collaborator - Robot on Rails worked with Red Queen Bio and OpenAI on AI-directed molecular-cloning experiments.

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Market context

Autonomous lab execution - Workflow - Undergrad executes scientific protocols and verifies steps with vision.
Lab robotics systems - Peer Group - Undergrad is a robotic system designed to execute scientific laboratory protocols.
Natural-language robot control - Capability - Robot on Rails accepts plain-language protocol instructions without custom workflow code.

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